HIGHLIGHTS
- who: Ju00falia Costa and collaborators from the Instituto Tecnologia Quu00edmica e Biolu00f3gica Antu00f3nio Xavier, Universidade Nova Lisboa have published the research work: Cerebrospinal Fluid Chitinases as Biomarkers for Amyotrophic Lateral Sclerosis, in the Journal: Diagnostics 2021, 11, 1210. of /2021/
- how: The authors analyzed the CSF of ALS patients by UHPLC-mass spectrometry to investigate potential products of CHIT1 activity. The raw HRAM (high-resolution accuratemass) data were analyzed using Compound Discoverer software v3.2 (Thermo Scientific). As external standard to validate the analysis the authors used monosaccharide N-glycolylneuraminic acid which is absent from . . .
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