Cgas inhibition alleviates alu rna-induced immune responses and cytotoxicity in retinal pigmented epithelium

HIGHLIGHTS

  • who: Jing Li from the Anti-p-, (ab76493) and anti-, (ab68481) were from Abcam have published the research work: cGAS inhibition alleviates Alu RNA-induced immune responses and cytotoxicity in retinal pigmented epithelium, in the Journal: (JOURNAL)
  • what: The authors report that targeting GMP-AMP (cGAMP) synthase (cGAS) alleviates RNA-induced immune responses and cytotoxicity in The authors explored whether these cGAS-inhibiting reagents could be used to ameliorate the Alu RNAs-induced immune_responses and cell death in RPE.
  • how: The results showed that the pretreatment of EGCG significantly suppressed the DNA-induced . . .

     

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