Chac1 as a novel contributor of ferroptosis in retinal pigment epithelial cells with oxidative damage

HIGHLIGHTS

• who: Ye Liu and colleagues from the Zhejiang University, Hangzhou, China have published the paper: CHAC1 as a Novel Contributor of Ferroptosis in Retinal Pigment Epithelial Cells with Oxidative Damage, in the Journal: (JOURNAL)
• what: This study demonstrated for the first time the upregulation of Chac1 in oxidative damaged RPE cells, while the silencing of Chac1 significantly ameliorated ferroptosis via the inhibition of glutathione depletion.
• how: These data indicated data indicated that Chac1 contributes to ferroptosis by regulation of GSH metabolism in that Chac1 contributes to ferroptosis by regulation of GSH metabolism in . . .
  

   

  

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