Chalcogen bond-guided conformational isomerization enables catalytic dynamic kinetic resolution of sulfoxides

HIGHLIGHTS

  • who: Jianjian Liu from the (UNIVERSITY) have published the paper: Chalcogen bond-guided conformational isomerization enables catalytic dynamic kinetic resolution of sulfoxides, in the Journal: (JOURNAL)
  • what: The authors report a catalytic strategy for asymmetric access to chiral sulfoxides by employing conformational isomerization and chalcogen bonding interactions.
  • how: The results showed that the chalcogen bond strength of 1c and 1i were 3.56 and 4.27 kcal/mol respectively (see Supplementary Fig 1 for details). The experimental method and data generated in this study are provided in the Supplementary Information file.
 

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