HIGHLIGHTS
- who: Hesham ElAbd and collaborators from the University of Pretoria, South Africa have published the research: Challenges and opportunities in analyzing and modeling peptide presentation by HLA-II proteins, in the Journal: (JOURNAL)
- what: Although the experiments proposed above would provide much-needed insights into the role of proteases in shaping HLAII immunopeptidomes, it is only one piece of the larger puzzle as it only delineates the determinants of the digestive process. In this perspective the authors aimed at highlighting gaps in the understanding of peptide presentation and T_cell activation, and discussed approaches for further . . .
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