Challenges and progress toward tumor-targeted therapy by systemic delivery of polymer-complexed oncolytic adenoviruses

HIGHLIGHTS

  • who: Thavasyappan Thambi from the (UNIVERSITY) have published the research: Challenges and progress toward tumor-targeted therapy by systemic delivery of polymer-complexed oncolytic adenoviruses, in the Journal: (JOURNAL) of 20/04/2022
  • what: The review attempts to provide future directions in the design of efficient polymer-Ad vectors, briefly discussing the challenges 1322 toward the clinical development of polymer-Ad formulations, including biosafety and regulatory considerations, and how these challenges can be addressed. Studies were carried out to examine the in_vivo fate of pHPMAmodified Ads . This study examines the in_vivo efficacy of DWP418-PEG . . .

     

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