Challenges of using external data in clinical trials- an illustration in patients with covid-19

HIGHLIGHTS

  • who: Sylvie Chevret from the France France have published the research: Challenges of using external data in clinical trials- an illustration in patients with COVID-19, in the Journal: (JOURNAL) of July/17,/2020
  • what: The authors focused on the subset of mechanically ventilated patients, given the marked reported benefit in this subset over usual care, from the previously published Recovery trial (NCT04381936) . The authors then aimed to compare the effect of the two dosages; this was indeed the aim of the Covidicus trial. Given the obvious differences across historical and current trials, notably in . . .

     

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