Chaperone requirements for de novo folding of saccharomyces cerevisiae septins

HIGHLIGHTS

  • who: Daniel Hassell and colleagues from the Facility of the University of Colorado Anschutz Medical CampusSamples were have published the research: Chaperone Requirements for De Novo Folding of Saccharomyces cerevisiae Septins, in the Preprint: biorxiv of 31/03/2022
  • what: The authors explore in greater detail chaperonin requirements for efficient septin synthesis and folding. In this experiment Bpa incorporation was much less efficient, and very little full-length protein was made. Based on the yeast septin-chaperone interaction results (Denney et_al, 2021; Johnson et_al, 2015), the authors focused on ClpB (homolog of the disaggregase Hsp104 . . .

     

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