Characterisation of an atrx conditional knockout mouse model: atrx loss causes endocrine dysfunction rather than pancreatic neuroendocrine tumour

HIGHLIGHTS

• who: Tiago Bordeira Gaspar et al. from the Instituto Investigação e Inovação Saúde (i S), University of, Universidade Federal do Rio Janeiro, Rio Janeiro, Brazil have published the paper: Characterisation of an Atrx Conditional Knockout Mouse Model: Atrx Loss Causes Endocrine Dysfunction Rather Than Pancreatic Neuroendocrine Tumour, in the Journal: (JOURNAL)
• what: The authors aimed to provoke telomere interference by administering the G4 stabiliser BRACO-19 to AtrxKO mice. The primary goal in this work was to assess the potential tumourigenic effect of this genetic alteration. The authors report, for the first . . .
  

   

  

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