HIGHLIGHTS
- who: Christopher J Tonkin and colleagues from the Walter and Eliza Hall Institute of Medical Research, Parkville, Australia have published the research work: Characterisation of the OTU domain deubiquitinase complement of Toxoplasma gondii, in the Journal: (JOURNAL)
- what: The authors were unable to determine substrates for TgOTUD3C or TgOTU10.
- how: Combining prior studies and further sequence annotation the authors identified 14 OTU DUBs in Toxoplasma a main difference to previous studies was the reannotation of OTUD1 orthologues (Fig 1). As a first test for reactivity with ubiquitin the authors used Ub-propargylamine (Ub . . .
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