Characteristics of cation binding to the i domains of lfa-1 and mac-1

HIGHLIGHTS

• who: David W. Griggs from the (UNIVERSITY) have published the article: Characteristics of Cation Binding to the I Domains of LFA-1 and MAC-1, in the Journal: (JOURNAL) of February/10,/1998
• what: The authors show that the purified recombinant I domain of LFA-1 (aLI) binds cations, but with significantly different characteristics compared with the I domain of MAC-1 (aMI). In the work described herein, the authors compared the cation binding properties of purified recombinant aL and aM I domains. The authors speculate that the Ca21/Mn21binding_site in aLI may represent an . . .
  

   

  

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