Characteristics of the immunogenicity and tumor immune microenvironment in her2-amplified lung adenocarcinoma

HIGHLIGHTS

  • who: Qinyang Wang from the Temple University, United States have published the Article: Characteristics of the immunogenicity and tumor immune microenvironment in HER2-amplified lung adenocarcinoma, in the Journal: (JOURNAL)
  • how: The authors conducted an integrative analysis that incorporated PD-L1 expression TMB MSI status immunerelated and immune cell-type GEPs and measures of TILs from cohorts of TCGA database as well as internal data and patient tumor specimens from 3 hospitals. In the TCGA cohort following previous experimental procedures RNA-sequencing (RNA-seq) data were analyzed using the R package edgeR and normalized by . . .

     

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