Characterization of an intelectin-1 (itln1) knockout mouse model

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  • who: Eric B. Nonnecke from the Institute of Subtropical Agriculture (CAS), China University of British Columbia have published the paper: Characterization of an intelectin-1 (Itln1) knockout mouse model, in the Journal: (JOURNAL)
  • what: The authors report here the development and analysis of mice harboring the Itln1-targeted trapping allele (designated Itln1trap), where Itln1 expression is hypomorphic and the endogenous Itln1 promoter drives LacZ expression. The authors demonstrated similar evidence for mouse Itln1 oligomerization, whereby in western blot analysis under nonreduced but denaturing conditions, a hexameric species was evident. The authors investigated the effect of . . .

     

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