Characterization of b-cell and t-cell responses to a tetravalent dengue purified inactivated vaccine in healthy adults

HIGHLIGHTS

• who: Heather Friberg from the Both studies were phase I, randomized, placebo-controlled, and observer blindThe design, inclusion/exclusion criteria and primary objectives for both trials have been previously described in detail12, . Briefly, the study in the predominantly dengue-naive population (NCT01666652) was conducted at the Clinical Trials Center at the Walter Reed Army Institute of Research (WRAIR), Silver Spring, Maryland, United States and enrolled healthy male and female adults between , and , years of age. The second trial (NCT01702857) was conducted at the University of Puerto Rico Medical Sciences Campus, Puerto Rico Clinical and Translational Research Consortium . . .
  

   

  

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