Characterization of light chain c-terminal extension sequence variant in one bispeci c antibody

HIGHLIGHTS

  • who: LC-/ and collaborators from the University of Foggia, Italy have published the paper: Characterization of light chain c-terminal extension sequence variant in one bispeci c antibody, in the Journal: (JOURNAL)
  • what: The authors characterized one LC extension sequence variant in the bispecific antibody cell pools.
  • future: Different cell pools with the same codon produced different percentages of variants which indicated the codon might not be the only influencing factor and more studies should be performed to reveal the exact splicing mechanism. transcription element to enhance the expression of plasmids in transfected . . .

     

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