Characterization of peptaibols produced by a marine strain of the fungus trichoderma endophyticum via mass spectrometry, genome mining and phylogeny-based prediction

HIGHLIGHTS

SUMMARY

Although it is possible to make a prediction of the possible nonribosomal peptides (NRPs) based on the adenylation domains, it is still difficult to accurately predict which of these putative NRPs are correct, mainly due to the post-assembly modifications of amino_acids carried out by decoration genes present in the BGC. Although a good coverage 10 of 17 of fragments was observed in terms of amino_acid sequence, fragments b1 and b2 could not be seen in the MS/MS experiments. When carrying out the analysis of the phylogeny data, it was observed that module . . .

 



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