Characterization of rna polymerase ii trigger loop mutations using molecular dynamics simulations and machine learning

HIGHLIGHTS

• who: Bercem Dutagaci and colleagues from the Department Molecular and Cell Biology, University California Merced, Merced, California, United have published the article: Characterization of RNA polymerase II trigger loop mutations using molecular dynamics simulations and machine learning, in the Journal: (JOURNAL) of August/15,/2022
• what: This study provides a systematic characterization the structural 1 / 27 __NEWPAGE__PLOS COMPUTATIONAL BIOLOGY data is presented in Figs 1-6 and S1-S26 and S1 and S2 Tables. The authors applied ML approaches to interpret genetic fitness values, sequence information, and MD simulation data to predict and characterize TL . . .
  

   

  

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