Characterization of stable pyrazole derivatives of curcumin with improved cytotoxicity on osteosarcoma cell lines

HIGHLIGHTS

  • who: Giordana Feriotto and collaborators from the Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Ferrara, Italy have published the Article: Characterization of Stable Pyrazole Derivatives of Curcumin with Improved Cytotoxicity on Osteosarcoma Cell Lines, in the Journal: Life 2023, 13, x FOR PEER REVIEW of /2023/
  • what: The authors investigated the stability of CUR-derivatives in biological fluids and drug-like characteristics, as well as their cytotoxicity and ability to trigger apoptosis on OS cells.
  • how: The authors considered the replacement of the bis-ketone with pyrazole or O-substituted . . .

     

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