Characterization of the newly established homoharringtonine- (hht-) resistant cell lines and mechanisms of resistance

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  • who: Fenglin Li et al. from the Department Hematology, The Affiliated People`s Hospital Ningbo University, Ningbo, China have published the article: Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance, in the Journal: Journal of Oncology 40 of 30/08/2022
  • what: The main reasons for poor prognosis in AML patients are primary drug resistance and disease relapse. Based on the above-mentioned background, the authors aimed to establish HHT-resistance AML cell lines with different RIs via exposure to gradually increasing HHT concentrations. The authors focused on upregulated . . .

     

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