Characterization of tumor microenvironment and programmed death-related genes to identify molecular subtypes and drug resistance in pancreatic cancer

HIGHLIGHTS

• who: March et al. from the Xiangya Hospital, Central South University, China have published the paper: Characterization of tumor microenvironment and programmed death-related genes to identify molecular subtypes and drug resistance in pancreatic cancer, in the Journal: (JOURNAL)
• what: In this study, PAAD samples were described as three different TME molecular subtypes (C1, C2, C3) using consistent clustering based on ssGSEA scores of 29-TME signature in the PACA-AU cohort. Survival analysis in this study showed that patients with C1 molecular subtype had higher CAF signature and clinicopathological stage, and that those with . . .
  

   

  

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