Checkpoint kinase 1 is a key signal transducer of dna damage in the early mammalian cleavage embryo

HIGHLIGHTS

  • who: Vladimu00edr Baran and Alexandra Mayer from the Institute of Animal Physiology, Centre of Biosciences, Slovak Academy of Sciences, u0160oltu00e9sovej, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University have published the paper: Checkpoint Kinase 1 Is a Key Signal Transducer of DNA Damage in the Early Mammalian Cleavage Embryo, in the Journal: (JOURNAL)
  • what: In this review the authors focus on the Chk1 kinase as a key transduction factor in monitoring the integrity of DNA molecules during early embryogenesis. Subcellular abnormalities that often occur after in_vitro fertilization are associated with DNA damage . . .

     

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