Checkpoint molecules on infiltrating immune cells in colorectal tumor microenvironment

HIGHLIGHTS

  • who: Noha M. Elemam and Maha Saber-Ayad from the Tufts University School of Medicine, United States have published the research: Checkpoint molecules on infiltrating immune cells in colorectal tumor microenvironment, in the Journal: (JOURNAL)
  • what: In this review, the authors aim to discuss the various cellular immune components, focusing on the impact of immune checkpoint molecules on the CRC TME. time.
  • how: These results indicated that tumor-derived matrices caused an antiinflammatory M2-like macrophage polarization significantly .

SUMMARY

    The co-inhibitory receptor programmed death-1 (PD-1), also . . .

     

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