Chemical and enzymatic modifications of 5-methylcytosine at the intersection of dna damage, repair, and epigenetic reprogramming

HIGHLIGHTS

  • who: Tuvshintugs Baljinnyam et al. from the Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas have published the research: Chemical and enzymatic modifications of 5-methylcytosine at the intersection of DNA damage, repair, and epigenetic reprogramming, in the Journal: PLOS ONE of August/29,/2022
  • what: In the studies , glycosylase excision of a target base generates an abasic site. In the studies reported here, cleavage bands observed in the absence of a glycosylase were used as a control and subtracted from the glycosylase generated band. In this study, oligonucleotides were characterized . . .

     

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