HIGHLIGHTS
- who: Takashi Sugiyama from the LaboratoryUniversity of have published the research: Chemical chaperones ameliorate neurodegenerative disorders in Derlin-1-deficient mice via improvement of cholesterol biosynthesis, in the Journal: Scientific Reports Scientific Reports
- how: The results showed that 4-PBA treatment increase the level of the active form of SREBP-2 in the cerebella of Derl1NesCre mice (Fig 2A B). One-way ANOVA and Fisher`s exact test followed by post hoc tests were conducted to compare three or more group means.
- future: Although further studies are needed to elucidate the precise molecular . . .
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