HIGHLIGHTS
- who: Assessment and collaborators from the Institute for Protein Research, Osaka University, Suita, Osaka, Japan have published the paper: Chemical-induced chromosome damage detection, in the Journal: (JOURNAL)
- what: In the present review, the authors focus on the methodologies and issues of the current genotoxicity detection methods and on strategies to improve the current methods, their biological relevance, and also the application of new methodologies to evaluate chemically induced chromosomal damage and DNA breaks that can lead to mutations and chromosome rearrangements.
- future: Investigations for in_vivo-in_vitro extrapolation are required to achieve a . . .
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