Chemogenetic disconnection between the orbitofrontal cortex and the rostromedial caudate nucleus disrupts motivational control of goal-directed action

HIGHLIGHTS

  • who: DREADDs and collaborators from the 021-A-14) at Primate Research Institute, Kyoto UniversityKyoto University, Inuyama, Japan have published the Article: Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action, in the Journal: (JOURNAL) of August/10,/2022
  • what: The authors show that following systemic administration of DREADD agonists, goal-directed behavior in monkeys was altered so that they became insensitive to differences in reward magnitude and satiation. For the experiment, the authors used a reward-size task, as described A B Time Bar touch . . .

     

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