Chemogenetic enhancement of camp signaling renders hippocampal synaptic plasticity resilient to the impact of acute sleep deprivation

HIGHLIGHTS

  • who: Significance Statement and colleagues from the Department of Neuroscience and Pharmacology, Carver College of Medicine, University of Iowa, Iowa City, IA , have published the paper: Chemogenetic Enhancement of cAMP Signaling Renders Hippocampal Synaptic Plasticity Resilient to the Impact of Acute Sleep Deprivation, in the Journal: (JOURNAL)
  • what: The authors build on these important experiments to investigate whether elevating hippocampal cAMP levels during SD would also provide resilience against deficits in synaptic plasticity. Using the same approach of virus-mediated expression of the DmOctb 1R in excitatory hippocampal neurons, the authors show that activation of . . .

     

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