Chemokine cxcl12 drives pericyte accumulation and airway remodeling in allergic airway disease

HIGHLIGHTS

  • who: Rebecca Bignold from the School of Biosciences, College of Health and Life Sciences, Aston University, Birmingham , ET, UK have published the article: Chemokine CXCL12 drives pericyte accumulation and airway remodeling in allergic airway disease, in the Journal: (JOURNAL)
  • what: Building on previous work showing that pericytes uncouple from the vasculature and migrate to the inflamed airway wall and thereby contribute to airway remodeling, this study aimed to elucidate the means by which pericytes migrate to sites of inflammation and fibrosis in the lung. This study showed that CXCL12 contributes to the differentiation of bone . . .

     

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