Chi sequences switch the recbcd helicase-nuclease complex from degradative to replicative modes during the completion of dna replication

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  • who: Nicklas A. Hamilton from the Dept Biology Portland State UniversityDept Biology Portland State University have published the Article: chi sequences switch the RecBCD helicase-nuclease complex from degradative to replicative modes during the completion of DNA replication, in the Journal: (JOURNAL)
  • what: The authors propose that chi serves functionally differentiate DNA ends created during completion which require degradation from those created by chromosomal double-strand breaks which require resynthesis. The aim of this strand bias is difficult to reconcile with classical models of double-strand break repair, since a break would have two double . . .

     

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