Chibby suppresses aerobic glycolysis and proliferation of nasopharyngeal carcinoma via the wnt/β-catenin-lin28/let7-pdk1 cascade

HIGHLIGHTS

  • who: Cheng-fu Cai from the Teaching Hospital of Fujian Medical University, Xiamen, China have published the paper: Chibby suppresses aerobic glycolysis and proliferation of nasopharyngeal carcinoma via the Wnt/β-catenin-Lin28/let7-PDK1 cascade, in the Journal: (JOURNAL)
  • what: Taken together, our findings identified Chibby as a negative regulator of proliferation that suppresses NPC aerobic glycolysis via the inhibition of Wnt/β-catenin signaling in_vitro and in_vivo.
  • how: The results indicated that the cellular glucose uptake and lactate production in a culture medium were significantly reduced (Fig 2b c). The results showed that . . .

     

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