Chikungunya patient transcriptional signatures faithfully recapitulated in a c57bl/6j mouse model

HIGHLIGHTS

  • who: Cameron R. Bishop from the Federal University of Rio Grande do Sul, Brazil have published the Article: Chikungunya patient transcriptional signatures faithfully recapitulated in a C57BL/6J mouse model, in the Journal: (JOURNAL)
  • what: Using this method, the authors show that the C57BL/6J CHIKV mouse model provides a reliable and representative system in which to study CHIKV immunopathology and evaluate new treatments. This model has been used to investigate the virology, immunobiology and immunopathology of CHIKV infections . The authors provide a series of bioinformatic approaches that illustrate a validation process for the adult . . .

     

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