HIGHLIGHTS
- who: Lien De Caluwé et al. from the Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago have published the article: Chikungunya Virus’ High Genomic Plasticity Enables Rapid Adaptation to Restrictive A549 Cells, in the Journal: Viruses 2022, 14, 282. of 26/01/2022
- what: The authors applied viral passaging to adapt CHIKV to productive replication in restrictive A549 cells and subsequently characterized the adaptive mutations in the viral genome. When the authors compare the relative binding of the viruses to A549 and Vero cells, a slightly increased, although not significant, attachment . . .
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