Chimeric natural products derived from medermycin and the nature-inspired construction of their polycyclic skeletons

HIGHLIGHTS

  • who: Shupeng Yin from the (UNIVERSITY) have published the research work: Chimeric natural products derived from medermycin and the nature-inspired construction of their polycyclic skeletons, in the Journal: (JOURNAL) of 23/08/2021
  • what: The authors report eight chimeric medermycin-type natural products with unusual polycyclic skeletons. The authors show the discovery of eight chimeric medermycin-type polyketides, chimedermycins A-H , from the strain OUCMDZ4982.
  • how: The results showed that the metabolites of strain OUCMDZ-4982 exhibit significant antibacterial activity against Staphylococcus aureus (SA) and methicillin-resistant Staphylococcus aureus (MRSA). The antibacterial . . .

     

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