Chimeric virus-like particles and capsomeres induce similar cd8+ t cell responses but differ in capacity to induce cd4+ t cell responses and antibody responses

HIGHLIGHTS

• who: David J. Pattinson and Denise L. Doolan from the University of Oxford, United Kingdom have published the research work: Chimeric Virus-Like Particles and Capsomeres Induce Similar CD8+ T Cell Responses but Differ in Capacity to Induce CD4+ T Cell Responses and Antibody Responses, in the Journal: (JOURNAL)
• what: The characterization of VLPs for this project has been previously reported . The authors show that capsomere and VLP platforms induced similar levels of CD8+ T_cell responses but the capsomeres were significantly better at inducing epitopespecific CD4+ T_cell responses than VLPs.

SUMMARY

 



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