Chir99021, trough gsk-3 targeting, reduces epithelioid sarcoma cell proliferation by activating mitotic catastrophe and autophagy

HIGHLIGHTS

• who: Sabino Russi and colleagues from the UOC Clinical Pathology, Altamura Hospital, Altamura, Italy Department of Biology, University of Naples Federico II, Naples, Italy have published the article: CHIR99021, trough GSK-3 Targeting, Reduces Epithelioid Sarcoma Cell Proliferation by Activating Mitotic Catastrophe and Autophagy, in the Journal: (JOURNAL) of 30/Nov/2020
• what: The authors combined bioinformatics analyses and in-vitro validation to explore several multitarget chemical inhibitors as potential ES drugs using the cancerRXgene database , which contains drug response and genomics data of a large cell lines collection. Among them, the authors focused on . . .
  

   

  

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