HIGHLIGHTS
- who: Paola Brun et al. from the Department of Molecular Medicine, University of Padova, Via AGabelli, Padova, Italy have published the article: Chitosan Covalently Functionalized with Peptides Mapped on Vitronectin and BMP-2 for Bone Tissue Engineering, in the Journal: Nanomaterials 2021, 11, 2784. of 15/Oct/2021
- what: In the literature, many studies have demonstrated the benefits deriving from chitosan's biofunctionalization with RGD ; nevertheless, in this work, a nonapeptide called HVP (FRHRNRKGY) deriving from human vitronectin is proposed, as, differently from RGD, it shows an osteoblast-selective adhesive mechanism involving proteoglycan-mediated interactions . . .
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