Chlamydia trachomatis requires functional host-cell mitochondria and nadph oxidase 4/p38mapk signaling for growth in normoxia

HIGHLIGHTS

  • who: Jeewan Thapa from the University of South China, China have published the Article: Chlamydia trachomatis Requires Functional Host-Cell Mitochondria and NADPH Oxidase 4/p38MAPK Signaling for Growth in Normoxia, in the Journal: (JOURNAL)
  • what: In contrast to hypoxia, CtL2 requires functional Mt with NOX4/ p38MAPK-mediated signaling for its growth under normoxia.
  • how: This result was consistent with the previous finding that in contrast to other NOXs NOX4 is highly expressed in cellular membrane in vascular cells or endothelial cells (Ago et_al 2004 Griendling 2004).
  • future: Meanwhile further study . . .

     

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