Chloroquine-induced masking of a lipid that promotes ferriprotoporphyrin ix dimerization in malaria*

HIGHLIGHTS

  • who: Coy D. Fitch from the Erythrocytes were obtained from young male Swiss mice infected with chloroquine-susceptible Pberghei , parasites when their parasitemias reached ⬃, parasites per , erythrocytes, usually on day , or , of infection. In young mice, this parasite infects erythrocytes of all ages, and it produces an asynchronous infection. Male mice weighing ⬃, g were purchased from Harlan-Teklad (Madison, WI) for these experiments, and they were infected by intraperitoneal passage of erythrocytes infected with ⬃, parasites. Their care was in accord with St. Louis University policies. When treated with chloroquine, each mouse received , ␮mol of intraperitoneally , h before . . .

     

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