Choice of alternative polyadenylation sites, mediated by the rna-binding protein elavl3, plays a role in differentiation of inhibitory neuronal progenitors

HIGHLIGHTS

  • who: Giorgio R. Merlo from the Technologia, Italy University of Colorado Boulder have published the Article: Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors, in the Journal: (JOURNAL)
  • what: The authors report transcriptome-wide changes of the length of 30 UTR during differentiation of mouse adherent neural stem (ANS) cells, a model of differentiation of GABAergic inhibitory neurons (Pollard et_al, 2006; Paina et_al, 2011). The authors show that in a model of_(mammalian) neural progenitors the depletion of Elavl3 causes a shift . . .

     

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