HIGHLIGHTS
- What: The animals displayed improved performance and enhanced long-term potentiation after the treatment of CCKBR Conclusions Here the authors provide more evidence to support the role of CCK in learning and memory and its potential to treat AD. This study demonstrated that CCK-/- and aged 3xTg AD mice develop impairments not only behaviourally in the MWM and NOR tests but also physiologically in the neuroplasticity assay.
- Who: Nan Zhang from the All experimental procedures were conducted in accordance with the Animal Subjects Ethics Sub-Committees of the City University of Hong Kong, (C57/BL . . .
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