HIGHLIGHTS
- who: Gibson et_al and colleagues from the (UNIVERSITY) have published the paper: Cholesterol- dependent activity of dapsone against non- replicating persistent mycobacteria, in the Journal: (JOURNAL)
- what: The authors report a method of in vitro analysis of physiologically relevant non-u00adreplicating persistence (NRP) utilizing cholesterol as the sole carbon source alongside hypoxia as a driver of Mycobacterium bovis BCG into the NRP state. The authors utilized the model organism Mycobacterium bovis BCG Pasteur (MbBCG) to assess the drug susceptibility differences between mycobacteria in hypoxia-u00adinduced rich media NRP and hypoxic minimal cholesterol-u00adbased media NRP . . .
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