Cholesterol esters form supercooled lipid droplets whose nucleation is facilitated by triacylglycerols

HIGHLIGHTS

  • who: Calvin Dumesnil from the (UNIVERSITY) have published the research work: Cholesterol esters form supercooled lipid droplets whose nucleation is facilitated by triacylglycerols, in the Journal: (JOURNAL) of 27/07/2022
  • what: The authors show that CE forms supercooled droplets when the CE concentration in LDs is above 20% to TG and, in particular, liquid-crystalline phases when the fraction of CEs is above 90% at 37 u00b0C.
  • how: This result is consistent with the decrease in the number of nucleated LDs in the presence of DGAT inhibitors (Fig 2A-C). To simplify . . .

     

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