HIGHLIGHTS
- who: Naomi Sakashita from the DepartmentKumamoto University have published the research: Cholesterol loading in macrophages stimulates formation of ER-derived vesicles with elevated ACAT1 activity, in the Journal: (JOURNAL)
- what: To evaluate the ACAT1 enzyme activity based on ACAT1 protein content, the authors repeated the experiment shown in Fig 2B, loaded samples from OptiPrep fractions 4-6 and 9-11 that provided equal amount of ACAT activity in_vitro, and compared their relative ACAT1 protein content by immunoblotting. The authors propose the following scenario as a starting point for future investigations: recent evidence suggests that ER . . .
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