HIGHLIGHTS
- who: Atcharaporn Ontawong and collaborators from the Division of Physiology, School of Medical Sciences, University of Phayao, Phayao, Thailand have published the Article: Cholesterol-Lowering Effects of Asperidine B, a Pyrrolidine Derivative from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178: A Potential Cholesterol Absorption Inhibitor, in the Journal: Pharmaceuticals 2022, 15, 955. of 29/07/2022
- what: This study shows the promising and high-efficacy cholesterol-lowering action of a pyrrolidine derivative, asperidine B (preussin), by reducing intestinal cholesterol absorption, mediated by the activation of LXRα and interference with bile acid binding capacity.
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