Cholesterol metabolism: from lipidomics to immunology

HIGHLIGHTS

  • who: William J. Griffiths from the Swansea University, Swansea, Wales, United Kingdom have published the article: Cholesterol metabolism: from lipidomics to immunology, in the Journal: (JOURNAL)
  • what: The study performed by Diczfalusy et_al was aimed initially at identifying genes upregulated by LPS in mouse BMDM. Although the studies of Reboldi et_al and Dang et_al focused on the pathological consequence of LPS stimulation of macrophages in a setting of infection , cholesterol overload may have a role in driving in chronic diseases, such as obesity, metabolic syndrome, and atherosclerosis .
  • how: This leads to the next . . .

     

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