Cholesterol-stabilized membrane-active nanopores with anticancer activities

HIGHLIGHTS

  • who: Jie Shen from the (UNIVERSITY) have published the research: Cholesterol-stabilized membrane-active nanopores with anticancer activities, in the Journal: (JOURNAL) of 23/09/2022
  • what: The authors report on the examples of cholic acid-derived pore-formers, forming multimeric nanopores that become increasingly active in ion transport when the level of cholesterol increases from 0 to 50 mol% relative to the amount of lipid molecules present in the membrane.
  • how: Logically in the next step the authors therefore decided to look into poreforming capacity of four more molecules Ch-Cns (n . . .

     

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