Chromatin 3d structure, phase separation and disease

HIGHLIGHTS

  • who: In, and Finally, from the (UNIVERSITY) have published the research work: Chromatin 3D structure, phase separation and disease, in the Journal: (JOURNAL)

SUMMARY

    Published recent years, several studies have described dynamic changes in chromatin 3D structure and intracellular phase separation during disease development. These changes are closely related to alterations in gene_expression and therefore are proposed as one of the molecular basis of disease occurrence and cell fate determination. Dysregulation of LLPS and chromatin 3D structure can lead to many diseases, especially cancer, developmental disorders, and heart diseases. An increasing number of . . .

     

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