HIGHLIGHTS
- who: Hsiao P. J. Voon and Lee H. Wong from the University of Western Australia have published the Article: Chromatin mutations in pediatric high grade gliomas, in the Journal: (JOURNAL)
SUMMARY
The overwhelming majority of these histone point mutations occur on the histone variant H3.3 (83% of K27M mutations, 100% of G34R/V mutations), with rare mutations in canonical histone H3.1. frontiersin.org 10.3389/fonc.2022.1104129 are rapidly assembled behind the DNA replication fork. Histone H3.3 is encoded by two genes in the genome (H3F3A and H3F3B) and . . .
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