Chromatin remodeler chd7 targets active enhancer region to regulate cell type-specific gene expression in human neural crest cells

HIGHLIGHTS

• who: Tsukasa Sanosaka from the DepartmentKeio University have published the Article: Chromatin remodeler CHD7 targets active enhancer region to regulate cell type-specific gene expression in human neural crest cells, in the Journal: Scientific Reports Scientific Reports
• what: The authors aimed to compare CHD7-binding profiles in hiPSCs, hNECs, and hNCCs to identify hNCC-specific targets of CHD7. This study provides the first genome-wide mapping of CHD7 in hNCCs. The current analysis showed that these factors cooperated with CHD7 in hNCCs and that the regions co-occupied with TFAP2A, NR2F1/2, and CHD7 were . . .
  

   

  

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