Chromene derivatives as selective terra g-quadruplex rna binders with antiproliferative properties

HIGHLIGHTS

• who: Roberta Rocca and collaborators from the Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Department of Pharmacy, University of Napoli Federico II, Via DMontesano, Napoli, Italy have published the research work: Chromene Derivatives as Selective TERRA G-Quadruplex RNA Binders with Antiproliferative Properties, in the Journal: Pharmaceuticals 2022, 548 of /2022/
• what: In this work the three best candidates identified in the previous virtual screening campaign on bimolecular DNA/RNA G4s were investigated on the monomolecular Tel and G4s by means of molecular modelling simulations and in vitro and in cell . . .
  

   

  

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